Opportunity Information: Apply for PAR 23 099
Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional) (PAR 23-099) is an NIH grant opportunity designed to broaden and strengthen HIV/AIDS research that directly fits within the scientific areas supported by the National Institute on Deafness and Other Communications Disorders (NIDCD). The core goal is to stimulate new and expanded studies on how HIV, HIV-related conditions, and their prevention or treatment intersect with communication and sensory systems, specifically hearing, balance (vestibular function), taste, smell, voice, speech, and language. In practice, this means proposals should be solidly grounded in NIDCD mission space while clearly addressing important HIV/AIDS needs and gaps.
A key expectation of this announcement is alignment with the NIH Office of AIDS Research (OAR) HIV/AIDS research priorities. Applicants are expected to frame their specific aims in ways that connect to the broader NIH HIV/AIDS agenda, using OAR priorities as the organizing reference point for significance and impact. While the FOA text highlights the NIDCD-relevant domains (hearing, balance, taste, smell, voice, speech, language), it also signals that the strongest applications will not just study these systems in isolation. They will show why the work matters for HIV outcomes, quality of life, prevention, comorbidities, treatment optimization, or reducing health disparities among people affected by or at risk for HIV.
The mechanism is an R01, meaning it supports hypothesis-driven, investigator-initiated research projects of substantial scope. The FOA is labeled "Clinical Trial Optional," which allows either non-clinical-trial research (basic, translational, observational, or other human subjects research that does not meet NIH’s definition of a clinical trial) or projects that do include a clinical trial. However, if a clinical trial is proposed, the FOA limits support to low-risk clinical trials only. Applicants considering an intervention study should be prepared to justify why the trial is low risk, how safety will be monitored, and why the chosen design is appropriate for the HIV/AIDS question within an NIDCD-relevant domain.
The opportunity is categorized as a discretionary grant in the health area (CFDA 93.173) and is administered by the National Institutes of Health. It is broadly open to a wide range of applicant types, reflecting NIH’s intent to encourage participation across academic, nonprofit, governmental, and private-sector research ecosystems. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; non-federally recognized Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The FOA also explicitly calls out additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, and non-U.S. entities (foreign organizations). This broad eligibility is especially relevant for HIV/AIDS work, where community partnerships, implementation contexts, and global or territorial settings may be central to the research questions.
From a timing and administrative standpoint, the FOA was created on February 14, 2023, and lists an original closing date of January 7, 2026. The source information provided does not specify an award ceiling or the expected number of awards, so applicants typically need to look to the full FOA and NIH budget guidance to shape an appropriate project scope and budget request under the R01 framework. Because it is an R01, applicants should generally expect a competitive review process emphasizing scientific merit, rigor, feasibility, and alignment with institute priorities, along with the added expectation here that the HIV/AIDS components are clearly responsive to OAR priorities and meaningfully integrated with NIDCD mission areas.
Overall, this funding opportunity is aimed at investigators who can bring strong HIV/AIDS research questions into the sensory and communication sciences, whether by clarifying mechanisms of HIV-related dysfunction, improving detection or measurement of relevant impairments, developing or testing low-risk interventions, or addressing real-world barriers and disparities affecting hearing, vestibular function, chemosensory function, voice, speech, and language outcomes in populations impacted by HIV.Apply for PAR 23 099
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173.
- This funding opportunity was created on 2023-02-14.
- Applicants must submit their applications by 2026-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 23 099) also looked into and applied for these:
| Funding Opportunity |
|---|
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional) Apply for PAR 23 106 Funding Number: PAR 23 106 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional) Apply for RFA MD 23 004 Funding Number: RFA MD 23 004 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| AHRQ Improving Diagnostic Safety in Ambulatory Care: Strategies and Preventions (R18) Apply for RFA HS 23 011 Funding Number: RFA HS 23 011 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| Dissemination and Implementation of Equity-Focused Evidence-Based Interventions in Healthcare Delivery Systems (R18) Apply for RFA HS 23 002 Funding Number: RFA HS 23 002 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $2,500,000 |
| AHRQ Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors (R01) Apply for RFA HS 23 010 Funding Number: RFA HS 23 010 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| Supporting the Management of Substance Use Disorders in Primary Care and other Ambulatory Settings (R18) Apply for RFA HS 23 005 Funding Number: RFA HS 23 005 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $625,000 |
| Genomics Centers for Infectious Diseases (U19 Clinical Trial Not Allowed) Apply for RFA AI 23 015 Funding Number: RFA AI 23 015 Agency: National Institutes of Health Category: Health Funding Amount: $2,850,000 |
| Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk (U01 Clinical Trial Not Allowed) Apply for RFA MH 23 275 Funding Number: RFA MH 23 275 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Network to Promote Multidisciplinary Mechanistic and Translational Studies of Sickle Cell Disease Pain (U24, Clinical Trial Optional) Apply for RFA AT 24 001 Funding Number: RFA AT 24 001 Agency: National Institutes of Health Category: Health Funding Amount: $600,000 |
| Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Independent Clinical Trial Not Allowed) Apply for RFA AG 24 014 Funding Number: RFA AG 24 014 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Clinical Trial Required) Apply for RFA AG 24 015 Funding Number: RFA AG 24 015 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| NIMH Short Courses for Mental Health Related Research (R25 -Independent Clinical Trial Not Allowed) Apply for PAR 23 265 Funding Number: PAR 23 265 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed) Apply for PAR 23 263 Funding Number: PAR 23 263 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed) Apply for PAR 23 266 Funding Number: PAR 23 266 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Roybal Centers for Translational Behavioral Research on Dementia Care, Caregiver Support, and Prevention of Alzheimers Disease and Related Dementias (AD/ADRD) (P30 Clinical Trial Required) Apply for RFA AG 24 007 Funding Number: RFA AG 24 007 Agency: National Institutes of Health Category: Health Funding Amount: $750,000 |
| Edward R. Roybal Coordinating Center (R24 - Clinical Trial Not Allowed) Apply for RFA AG 24 008 Funding Number: RFA AG 24 008 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Roybal Centers for Translational Research on Aging (P30 Clinical Trial Required) Apply for RFA AG 24 006 Funding Number: RFA AG 24 006 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Biomedical Technology Optimization and Dissemination Center (BTOD)(RM1-Clinical Trial Not Allowed) Apply for PAR 23 110 Funding Number: PAR 23 110 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Coordination Center for the Models of Infectious Disease Agent Study (MIDAS) Program (R24 Clinical Trial Not Allowed) Apply for PAR 23 129 Funding Number: PAR 23 129 Agency: National Institutes of Health Category: Health Funding Amount: $900,000 |
| National Centers for Cryoelectron Microscopy (R24 Clinical Trial Not Allowed) Apply for PAR 23 118 Funding Number: PAR 23 118 Agency: National Institutes of Health Category: Health Funding Amount: $6,500,000 |
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