Opportunity Information: Apply for PA 17 285
The National Institutes of Health (NIH) grant opportunity titled "Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01)" (Funding Opportunity Number PA 17-285) supports research projects aimed at improving the scientific understanding of how people recover from Alcohol Use Disorder (AUD) and why relapse occurs, particularly in the context of treatment. It is an R01 mechanism, meaning it is intended for substantial, hypothesis-driven or otherwise rigorous research programs that can meaningfully advance knowledge in the alcohol treatment and recovery space. The overall emphasis is on encouraging applications that are especially innovative and highly significant, with a clear expectation that proposed studies will move beyond general outcome tracking to examine the underlying processes and mechanisms that shape recovery trajectories over time.
A central theme of the announcement is the idea that recovery is not a single event but a dynamic process that can unfold in different ways for different individuals and settings. The FOA highlights several priority areas that applicants are encouraged to address. One major topic is defining recovery itself, which can include clarifying what recovery means clinically and functionally, how it should be measured, and how definitions might differ across populations, treatment approaches, and time horizons. Another priority is developing and using new, innovative methods to study the precipitants of relapse. This includes research that can capture near-real-time risk factors, contextual triggers, and transitional periods when relapse is more likely, potentially using novel measurement strategies or analytic approaches that better reflect the day-to-day realities of recovery.
The FOA also calls for deeper work on mutual help and recovery mechanisms. This area covers research on how mutual-help involvement and peer-supported recovery pathways contribute to change, what specific components drive benefit, and for whom these approaches are most effective. In addition, the announcement encourages evaluations of recovery systems of care, which generally refers to coordinated, community- and service-based networks that support people after or alongside formal treatment. Research in this area can look at how system design, linkage to services, continuity of care, and community supports influence long-term outcomes. Finally, the FOA explicitly invites studies on extended treatment processes for AUD, recognizing that sustained care models, continuing care, and longer-term engagement strategies may be necessary to support lasting recovery and reduce relapse risk.
From an administrative and eligibility standpoint, this is a discretionary NIH grant in the health funding category, associated with CFDA 93.273. A wide range of applicant types are eligible, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education, where applicable); for-profit organizations other than small businesses; and small businesses. The opportunity also highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
At the same time, the announcement is explicit about restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In other words, this FOA is intended to fund U.S.-based research efforts without foreign components. The original closing date listed for this opportunity is January 24, 2018, and the FOA record indicates it was created on May 12, 2017. The award ceiling and expected award counts are not specified in the provided text, which is common in NIH listings when budgets depend heavily on project scope and standard NIH policy rather than a single fixed cap.
In practical terms, the opportunity is designed for research teams that can rigorously study how recovery happens over time, identify actionable relapse predictors, and test or evaluate care approaches that can be implemented in real-world treatment and recovery ecosystems. Strong proposals under this FOA would typically be expected to have clear conceptual models of recovery and relapse, thoughtful measurement strategies, and methods capable of capturing change processes rather than only end-point outcomes, with a clear line of sight to improving treatment and long-term recovery support for people with AUD.Apply for PA 17 285
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
- This funding opportunity was created on 2017-05-12.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the title of this NIH funding opportunity?
The funding opportunity is titled "Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01)".
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA 17-285.
Which agency is offering this grant opportunity?
This opportunity is offered by the National Institutes of Health (NIH).
What type of grant mechanism is this?
This opportunity uses the R01 mechanism, which is intended for substantial, rigorous research programs (often hypothesis-driven) that can meaningfully advance scientific knowledge.
What is the overall purpose of this FOA?
The overall purpose is to support research that improves scientific understanding of how people recover from Alcohol Use Disorder (AUD) and why relapse occurs, particularly in the context of treatment.
What does the FOA emphasize about the concept of recovery?
The FOA emphasizes that recovery is not a single event but a dynamic process that can unfold in different ways across individuals and settings, and over time.
What kinds of studies is NIH encouraging under this FOA?
NIH is encouraging applications that are especially innovative and highly significant, with studies expected to move beyond general outcome tracking to examine the underlying processes and mechanisms shaping recovery trajectories.
Is this FOA focused only on outcomes (e.g., abstinence rates), or also on mechanisms?
The emphasis is on going beyond outcomes alone and examining processes and mechanisms that shape recovery and relapse over time (for example, factors and transitions that influence trajectories).
What are the priority research areas highlighted in the announcement?
The FOA highlights several priority areas, including:
- Defining recovery (clinical/functional meaning, measurement, and how definitions vary across populations and time horizons)
- Innovative methods to study relapse precipitants (near-real-time risk factors, contextual triggers, high-risk transitional periods, and novel measurement/analytic strategies)
- Mutual help and recovery mechanisms (how mutual-help involvement and peer-supported pathways contribute to change, what components drive benefit, and for whom)
- Recovery systems of care (how coordinated community/service networks, linkage, continuity, and supports influence long-term outcomes)
- Extended treatment processes for AUD (continuing care, sustained care models, and longer-term engagement to support lasting recovery)
What does "defining recovery" mean in the context of this FOA?
It refers to research that clarifies what recovery means clinically and functionally, how it should be measured, and how definitions may differ by population, treatment approach, and time horizon.
What kinds of relapse-related research does the FOA encourage?
The FOA encourages research that develops and uses new, innovative methods to study relapse precipitants, including approaches that capture near-real-time risk factors, contextual triggers, and transitional periods when relapse is more likely.
Does the FOA mention specific approaches for capturing relapse risk in day-to-day life?
Yes. It explicitly points to the value of methods that better reflect the day-to-day realities of recovery, including novel measurement strategies and analytic approaches capable of capturing near-real-time changes and context.
What does the FOA mean by "mutual help and recovery mechanisms"?
This refers to research on how mutual-help involvement and peer-supported recovery pathways contribute to change, identifying which components drive benefit and for whom these approaches are most effective.
What are "recovery systems of care" in this FOA?
Recovery systems of care are described as coordinated, community- and service-based networks that support people after or alongside formal treatment. The FOA encourages studying how system design, linkages, continuity of care, and community supports influence outcomes.
Does this FOA support research on longer-term or continuing care models?
Yes. The FOA explicitly invites studies on extended treatment processes for AUD, including sustained care models, continuing care, and longer-term engagement strategies to reduce relapse risk and support lasting recovery.
What is the funding category for this opportunity?
The opportunity is listed in the health funding category.
Is this a discretionary grant?
Yes. It is described as a discretionary NIH grant.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA 93.273.
Who is eligible to apply?
A wide range of applicants are eligible, including:
- State, county, city, or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Tribal organizations (other than federally recognized tribal governments)
- Public housing authorities and Indian housing authorities
- Nonprofit organizations (with or without 501(c)(3) status), where applicable
- For-profit organizations (other than small businesses)
- Small businesses
Are any additional organization types specifically highlighted as eligible?
Yes. The FOA highlights additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply?
No. The announcement states that non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-domestic component under this FOA?
No. The FOA indicates that non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed if the applicant is a U.S. organization?
No. The FOA states that foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
What is the closing date listed for this opportunity?
The original closing date listed is January 24, 2018.
When was this FOA record created?
The FOA record indicates it was created on May 12, 2017.
Is there an award ceiling (maximum award amount) specified in the provided information?
No. The award ceiling is not specified in the provided text.
Is the expected number of awards specified?
No. The expected award counts are not specified in the provided text.
What types of proposals would likely be competitive under this FOA based on the description?
Based on the description, strong proposals would typically include a clear conceptual model of recovery and relapse, thoughtful measurement strategies, and methods capable of capturing change processes over time rather than only end-point outcomes, with a clear line of sight to improving treatment and long-term recovery support for people with AUD.
Does the FOA focus on real-world treatment and recovery settings?
Yes. The opportunity is framed around understanding recovery and relapse in the context of treatment and is oriented toward research that can inform approaches implementable within real-world treatment and recovery ecosystems (including systems of care and community supports).
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