NIDDK Centers for Diabetes Translation Research (P30 Clinical Trial Optional) | RFA DK 26 001

Opportunity Information: Apply for RFA DK 26 001

The NIDDK Centers for Diabetes Translation Research (CDTR) funding opportunity (RFA-DK-26-001) is a National Institutes of Health (NIH) P30 center grant designed to strengthen and speed up diabetes translation research, specifically across the T2 to T4 spectrum. In practical terms, it focuses on moving evidence from clinical discovery and early testing into real-world clinical practice, health systems, and community settings, and then studying how best to disseminate and implement proven interventions at scale. The overarching goal is to maximize the population-level impact of diabetes research by building a coordinated center that provides shared infrastructure, specialized expertise, and practical support services to investigators working on translation, dissemination, and implementation questions.

A central expectation of this program is that funded centers will operate through a set of shared cores that make research more efficient and more collaborative. Rather than supporting isolated projects, the CDTR model emphasizes cost-effective shared resources that increase productivity, create synergy among investigators, and generate new translational research ideas. These cores can include services such as methodology and study design support for pragmatic and implementation trials, community-engaged research capabilities, measurement and evaluation support, data and informatics resources, training and education offerings, and other specialized tools that help investigators move diabetes interventions into routine care and community practice.

Health equity and reduction of diabetes-related disparities are strongly emphasized. Applications are encouraged to incorporate novel methods and research approaches that directly address inequities in diabetes prevention, treatment, and outcomes across populations and settings. The announcement also allows for innovative cores that focus on other person-centered, community, or population health priorities, as long as applicants clearly justify how the resulting findings or strategies could be adapted to meaningfully inform disparity-reduction efforts. In other words, even if a core is not solely devoted to disparities, it should still have a plausible pathway to advancing equity-focused translation.

The NOFO also signals that a strong scientific base and partnership network are expected. Successful CDTR applications should reflect an ecosystem that includes academic investigators and diverse collaborators such as healthcare systems, community organizations, public health departments, and human services organizations. This collaborative structure is intended to ensure that interventions and implementation strategies are grounded in real-world needs and can be tested, refined, and scaled in the settings where people actually receive care and support.

In terms of administrative details, this is a discretionary grant mechanism with a funding activity category in health (and related food and nutrition areas) under CFDA 93.847. Clinical trials are listed as optional, which generally means the center may support trial-related translational and implementation work when appropriate, but a clinical trial is not required for every component. The original application closing date is June 10, 2025, and the opportunity was created on December 9, 2024. The provided listing does not specify an award ceiling or the anticipated number of awards in the excerpted fields.

Eligibility is broad and includes many types of domestic entities: state, county, and local governments; special districts; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The NOFO explicitly highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, it clearly excludes foreign participation in key ways: non-U.S. (foreign) organizations are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.

Overall, the opportunity is aimed at building robust, collaborative, equity-centered translation research centers that can help close the gap between what is known to work in diabetes care and what is consistently delivered in clinics, health systems, and communities, with shared cores and partnerships designed to make that translation faster, more rigorous, and more impactful at the population level.

• The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "NIDDK Centers for Diabetes Translation Research (P30 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on 2024-12-09.
• Applicants must submit their applications by 2025-06-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA DK 26 001

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