Opportunity Information: Apply for SFOP0005182

The Global Biosecurity Engagement Activities opportunity (Funding Opportunity Number SFOP0005182) is a U.S. Department of State program run by the Bureau of International Security and Nonproliferation (ISN), specifically its Office of Cooperative Threat Reduction (ISN/CTR). It sits under the broader Global Threat Reduction (GTR) portfolio and is implemented through a cooperative agreement, meaning awardees should expect substantial coordination with the government during planning, execution, and reporting. The core purpose is to reduce biological threats internationally by strengthening how countries and institutions manage dangerous pathogens, protect laboratories and related facilities, and support responsible life sciences work in ways that align with U.S. nonproliferation objectives and global health security goals.

At the center of this funding is the Biosecurity Engagement Program (BEP) mission: institutionalizing biorisk management best practices, improving security at life science institutions that handle risky materials, reducing the chance that scientists with dual-use knowledge could intentionally misuse pathogens, and encouraging adoption of international norms and requirements that discourage biological weapons development. The opportunity explicitly ties its objectives to major international frameworks, including United Nations Security Council Resolution 1540 (which focuses on preventing non-state actors from obtaining weapons of mass destruction), the Biological Weapons Convention, the World Health Organization International Health Regulations, and recognized technical standards such as CEN and ISO standards. In practical terms, this frames projects not only as technical capacity-building, but also as efforts that reinforce governance, compliance, and long-term international commitments around safe and secure biological work.

BEP funding is organized around three main pillars, with an emphasis on sustainability rather than one-off activities. The first pillar targets biosecurity and biosafety in laboratories and other life science settings. Typical activities under this pillar include technical consultations, formal risk assessments, and training courses intended to build durable in-country expertise and establish a lasting culture of laboratory biorisk management. This pillar also extends beyond labs into the security sector by supporting training for foreign law enforcement and security forces on how to detect, investigate, and disrupt potential bioterrorism plots. That law enforcement component signals that BEP is concerned not only with accidental risks and weak controls, but also with deliberate misuse and the need for operational readiness to respond to biothreat incidents.

The second pillar focuses on infectious disease detection and control, aiming to strengthen public health and veterinary health systems so they can identify outbreaks earlier, report them appropriately, and respond effectively. This includes building capacity across surveillance and reporting systems, laboratory and diagnostic capabilities, and outbreak management practices. The inclusion of veterinary health alongside human public health reflects the reality that many serious outbreaks are zoonotic and that strong biosecurity requires a One Health style approach that connects animal and human disease monitoring and response.

The third pillar is scientific engagement, designed to enhance global health security by building safe, secure, and sustainable bioscience capacity through joint scientific collaborations. These collaborations are framed as a way to prevent, detect, and respond to biological threats while also promoting responsible research practices and norms. In effect, this pillar uses collaborative science as both a capability-building tool and a risk-reduction strategy by shaping how research is conducted, managed, and safeguarded in partner countries.

Administrative details in the listing indicate this was a discretionary opportunity with CFDA number 19.033 and eligibility limited to nonprofit organizations with IRS 501(c)(3) status that are not institutions of higher education. The opportunity was posted June 12, 2018, with an original closing date of June 13, 2018. The public listing shows an award ceiling of 0 and expected awards of 0, which often reflects a posting that may have been informational, rapidly closed, or otherwise configured in the system without finalized award figures, rather than a clear indication that no funding would ever be made available. The sponsoring agency is the Department of State, Bureau of International Security-Nonproliferation, and the activity category is labeled "Other," consistent with the cross-cutting mix of security cooperation, public health capacity building, and scientific engagement described in the program narrative.

  • The Department of State, Bureau of International Security-Nonproliferation in the other (see text field entitled explanation of other category of funding activity for clarification) sector is offering a public funding opportunity titled "Global Biosecurity Engagement Activities" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 19.033.
  • This funding opportunity was created on Jun 12, 2018.
  • Applicants must submit their applications by Jun 13, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
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